Joint Pain Forum – News you can use!
Green tea compound touted as beneficial in
01 May 2007
present in green tea may prove beneficial in reducing pain and
inflammation associated with rheumatoid arthritis, a new study by the
University of Michigan Health System has indicated. Green tea is
already thought to be beneficial in fighting against heart disease as
well as cancer.
compound in question is called epigallocatechin-3-gallate (EGCG) and
was found to prevent the production of several molecules by the immune
system that play a crucial role in inflammation and cause joint damage
in patients suffering from rheumatoid arthritis.
isolated cells called synovial fibroblasts from patients with
rheumatoid arthritis and cultured them in a growth medium. Some
fibroblasts were also incubated in EGCG. Later on researchers exposed
the fibroblasts to pro-inflammatory cytokine IL-1b.
protein is known to cause joint damage in rheumatoid arthritis.
Fibroblasts unexposed to EGCG participated in molecular events that led
to the production of bone-destructive molecules, while EGCG treated
cells inhibited the production of bone-destroying molecules, the
research is a very promising step in the search for therapies for the
joint destruction experienced by people who have rheumatoid arthritis,”
said lead researcher Salah-uddin Ahmed of the Division of Rheumatology
at the U-M Health System. "The results from this study suggest that
EGCG may be of potential therapeutic value in regulating the joint
destruction in RA."
study was presented by Ahmed at the Experimental Biology 2007 meet on
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