Joint Pain Forum – News you can use!
Rheumatoid arthritis research points to genetic component
28th June 2007
Genetic variations and their effects is an emerging area of study and
within rheumatoid arthritis (RA). It offers a possible theory into the
widely varying patient responses to disease modifying anti-rheumatic
drugs. A geographical/ethnic trend seems to be present in Europe, where
RA is more common in the Anglo-Saxon population than in the
Mediterranean population. The US also shows a marked variation in
prevalence, which is suggestive of a genetic effect. At the other end
of the prevalence range, Japanese and Chinese studies have shown a
comparatively lower RA prevalence. However, it has been estimated that
these alleles account for only one-half of the genetic effect, leaving
the remaining factors to be discovered through continued research.
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