Joint Pain Forum – News you can use!
Vitamin D May Protect Against Rheumatoid
Women with highest levels of vitamin D intake are about one third less
likely to develop rheumatoid arthritis (RA) than women with the lowest
levels, findings from a new study suggest.
vitamin D is best known for its role in building bones, it may also
have effects on the immune system, senior author Dr. Kenneth G. Saag,
from the University of Alabama at Birmingham, and colleagues report in
the medical journal Arthritis and Rheumatism.
determine the effect of vitamin D intake on rheumatoid arthritis risk,
Saag's team analyzed data from nearly 30,000 women, between 55 and 69
years of age, who participated in the Iowa Women's Health Study. All of
the women were rheumatoid arthritis-free at study entry in 1986, and
vitamin D intake was ascertained through food frequency questionnaires.
During the 11-year follow-up period, 152 confirmed cases of rheumatoid
arthritis were identified, the investigators report.
and supplemental vitamin D intake were inversely linked with rheumatoid
arthritis risk, the authors found. High dietary (at least 290 IU/day)
and supplemental (at least 400 IU/day) intake were associated with 28
percent and 34 percent reductions, respectively, in the risk of
only the association between vitamin D supplement intake and rheumatoid
arthritis risk was statistically significant.
single food item high in vitamin D or calcium was strongly linked to
rheumatoid arthritis risk, the researchers point out. However, there
was a trend toward a lower rheumatoid arthritis risk with greater
intake of milk products.
the effects of vitamin D on the immune system are not yet fully
defined, "the results from this study suggest a possible role for
vitamin D in reducing the risk of an immunologic disorder," the authors
state. Further studies are needed to verify these findings, they add.
Map | CONTACT