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CombinatoRx Drops Arthritis Drug


Associated Press

CombinatoRx Inc. said Thursday it abandoned a potential drug to treat rheumatoid arthritis after clinical trials showed it did not significantly decrease inflammation. The Cambridge, Mass., biotechnology company said in a statement that while its CRx-150 compound significantly decreased pain in patients, it had no effect on inflammation.

"The level of activity observed with CRx-150 would not be competitive within the CombinatoRx product portfolio or the (rheumatoid arthritis) marketplace," said Alexis Borisy, CombinatoRx's president and chief executive, in a statement.

CombinatoRx's lead prospective treatment for the condition, CRx-102, has shown more promising results, he added.

Shares of CombinatoRx Inc. fell 10 cents to $6 in morning trading.

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