Glucosamine
and Chondroitin Are More Effective Than Pain Relievers
The GAIT Study Reveals the Latest Major
Glucosamine Clinical Trial Results...
Two
long-anticipated major clinical studies - the GAIT Study
and the GUIDE Trial - have recently found that
Glucosamine and Chondroitin Sulfate, work even better than common pain
killers.
With the ever
increasing interest on how to overcome the challenges of
living with osteoarthritis, particularly with two major prescription
drugs (Vioxx and Bextra) being removed from the market, along with
concerns about long term NSAID usage... these findings have never been
more relevant and important to arthritis sufferers and their care
givers.
.

GAIT
Study
(Glucosamine/Chondroitin Arthritis Intervention Trial) - Glucosamine
Effectiveness trial |
Additional
details:
Under the direction of the NIH (National Institutes of
Health), one of the world’s foremost medical research centers, 13
highly prestigious research universities in the United States performed
this randomized, double-blind, placebo controlled, parallel assignment,
efficacy study on over 1,500 osteoarthritis sufferers.
For 24 weeks, each participant was given a daily
dose of either:
• glucosamine hydrochloride
• chondroitin sulphate
• some combination of both
• 200 mg of the prescription painkiller celecoxib, a cox-2 drug
(Celebrex®)or a placebo
All patients' pain levels were evaluated at the beginning
of the study and again at the end of the four weeks. The Glucosamine
and Chondroitin combination was found to significantly reduce pain
compared to placebo and Celebrex® (celecoxib), using the WOMAC Pain
Index (Western Ontario and McMaster Osteoarthritis Index).
This study marks the very first time that a well designed
study of this scale has been done on a supplement and the results were
shocking to many but exactly what many Glucosamine users have know for
years.
This study was conducted by the National Institutes of Health at
thirteen distinguished colleges, using taxpayer’s – not a
manufacturer’s - dollars. This guaranteed and unbiased and reliable
result.
[Back to Top of Page]

GUIDE Trial - The
Glucosamine Unum-in-Die (Once a
Day) Efficacy (GUIDE) Trial |
At about the same time the University based GAIT study results
were released in the United States, an independent Hospital based
European study - known as the GUIDE Trial - released its
results. They too, showed the extraordinary benefits of glucosamine.
Highlights:
• After 24 weeks of monitoring osteoarthritis
sufferers, the study clearly showed superior effectiveness of the
glucosamine dietary supplement (even at half the dosage of the drug) on
many levels of discomfort and mobility.
• The study confirmed that glucosamine was shown to be more effective
than the most commonly used pain reliever, acetaminophen.
• “Glucosamine sulfate…might be the preferred symptomatic medication in
knee osteoarthritis.” Dr Herrero-Beaumont of the Fundacíón Jiménez Díaz
in Madrid, found glucosamine sulfate to be more effective than the
over-the-counter painkiller acetaminophen for joint discomfort.
• The study was done at multiple hospitals, was randomized to prevent
bias, tested against both placebo and real medications and no-one
(including the doctors) was aware of who was getting the placebo or the
Glucosamine.
• The Glucosamine Unum in Die Efficacy (GUIDE) trial took place in 13
different European hospitals and compared a 1,500mg daily dose of
glucosamine sulfate and a much larger 3,000 mg dose of the OTC drug
Acetaminophen (commonly found in Tylenol, Excedrin, and many others) to
a placebo in 318 patients.
[Back
to Top of Page]
Additional commentary and
what this means to you.
|
It
has taken over five years for the official results of these
well designed studies to finally scientifically prove the effectiveness
of Glucosamine Sulfate and Chondroitin Sulfate.
Now that glucosamine and chondroitin in combination
have been shown to work at least as well as Celebrex or NSAIDS, with a
far better safety profile, the question remains...
What
is your best glucosamine and
chondroitin option?
We have researched this question and have
presented our findings and
recommendations within the Natural
Remedies section.
[Back to Top of Page]

MEMBERS
AREA
| Site
Map | CONTACT
US
Privacy
| Terms

|